Cleaning is an ongoing process: Sievers® instruments are designed to help during each stage of the cleaning lifecycle

Cleaning Validation and Verification

Sievers provides a partnership to increase efficiency, process understanding, and confidence throughout the lifecycle of your cleaning validation program.

Efficiency. Streamline equipment release for production and shorten analysis times using the Sievers M9 Lab, Portable, or On-Line TOC Analyzers. As a non-specific method, TOC analysis simplifies method development and allows you to test not only for product removal, but also removal of excipients, degradants, and cleaning agents. Learn about moving from HPLC to TOC.

Process Understanding. Available in various models, Sievers M9 TOC Analyzers provide flexibility for your cleaning application, enabling you to quickly assess the process capability of cleaning and optimize critical parameters. In addition to the M9 Laboratory Analyzer, portable models can be used at-line, and the M9 On-Line can be attached to a CIP skid for real-time cleaning process trending, control, and equipment release. Learn about implementing TOC.

Confidence. Sievers M9 TOC Analyzers use membrane conductometric technology to accurately measure organics in rinse and online samples without interference from background substances. Beyond instrumentation you can trust, Sievers offers complete traceability of standards and vials, including the availability of Failure Analysis Reports, to help you efficiently resolve TOC out-of-specification (OOS) investigations when needed. See how Sievers is different.